The Vodacom URC match kicks off at 14h00 on Saturday and will be broadcast live on SuperSport, while tickets are available from Ticketpro from R50 each.
In the front row, hooker Scarra Ntubeni returns from injury and there is a rotational switch at tighthead prop, with Neethling Fouche starting and Frans Malherbe set to make an impact in the second half.
Deon Fourie is back in the starting line-up on the flank, while the only change in the backline sees Herschel Jantjies start at scrumhalf.
Warrick Gelant is also set to make his return from a replacements bench which also features Brok Harris and Junior Pokomela this week.
DHL Stormers head coach John Dobson said that his team are looking forward to what should be a match to remember as they look to make it six consecutive home wins and maintain their position at the top of the South African Shield.
“Any game between the DHL Stormers and the Vodacom Bulls is a big occasion and this one has all the makings of a classic," said Dobson.
“It is fantastic to have the likes of Scarra and Warrick back from injury for this game. Warrick is being managed carefully and will make a big impact from the bench as he did earlier in the season.
“Our team cannot wait to run out in front of our fans at DHL Stadium on Saturday and will be giving absolutely everything to get the result,” he added.
DHL Stormers: 15 Damian Willemse, 14 Seabelo Senatla, 13 Ruhan Nel, 12 Rikus Pretorius, 11 Leolin Zas, 10 Manie Libbok, 9 Herschel Jantjies, 8 Evan Roos, 7 Hacjivah Dayimani, 6 Deon Fourie, 5 Marvin Orie, 4 Adre Smith, 3 Neethling Fouche, 2 Scarra Ntubeni, 1 Steven Kitshoff (captain). Replacements: 16 Chad Solomon, 17 Brok Harris, 18 Frans Malherbe, 19 Connor Evans, 20 Ben-Jason Dixon, 21 Junior Pokomela, 22 Paul de Wet, 23 Warrick Gelant.